Selection against BALB/c strain cells in mouse chimaeras
نویسندگان
چکیده
منابع مشابه
Selection against BALB/c strain cells in mouse chimaeras
It has been shown previously that BALB/c strain embryos tend to contribute poorly to mouse aggregation chimaeras. In the present study we showed that BALB/c cells were not preferentially allocated to any extraembryonic lineages of mouse aggregation chimaeras, but their contribution decreased during the early postimplantation period and they were significantly depleted by E8.5. The development o...
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Chimaeric mice were obtained by injecting embryonic (CBA/H-T6 X PDE)F1 cells into PDE blastocysts. Three of 15 young were overt chimaeras. One female and one male chimaera survived to adulthood and after completion of test breeding, which demonstrated chimaerism in the germ cells of both, they were killed for study when aged 32 and 33 weeks respectively. Chromosome spreads were scored for the p...
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ژورنال
عنوان ژورنال: Biology Open
سال: 2018
ISSN: 2046-6390
DOI: 10.1242/bio.030189